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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KIF5C
All Species:
25.15
Human Site:
Y463
Identified Species:
39.52
UniProt:
O60282
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60282
NP_004513.1
957
109495
Y463
L
A
S
T
R
R
D
Y
E
K
I
Q
E
E
L
Chimpanzee
Pan troglodytes
XP_525938
860
98662
L422
N
E
Q
L
T
D
E
L
A
Q
K
T
T
T
L
Rhesus Macaque
Macaca mulatta
XP_001082054
860
98340
L422
N
E
Q
L
T
D
E
L
A
Q
K
T
T
T
L
Dog
Lupus familis
XP_533351
955
109129
Y462
L
A
S
T
R
R
D
Y
E
K
I
Q
E
E
L
Cat
Felis silvestris
Mouse
Mus musculus
P28738
956
109222
Y462
L
A
S
T
R
R
D
Y
E
K
I
Q
E
E
L
Rat
Rattus norvegicus
Q6QLM7
1027
116897
N463
L
V
S
T
R
G
D
N
E
K
V
Q
R
E
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508129
965
109909
Q467
L
A
S
T
R
R
D
Q
D
N
M
Q
A
E
L
Chicken
Gallus gallus
Q90640
1225
138905
I567
Q
S
Q
Y
Q
T
N
I
K
D
L
E
L
E
V
Frog
Xenopus laevis
Q91784
1226
138905
I564
Q
S
E
Y
L
N
N
I
K
H
L
E
S
E
V
Zebra Danio
Brachydanio rerio
NP_001116747
985
113653
Y459
L
A
S
T
R
R
D
Y
E
K
I
Q
E
D
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P17210
975
110381
Y483
I
A
N
A
R
R
E
Y
E
T
L
Q
S
E
M
Honey Bee
Apis mellifera
XP_395236
988
112484
Y484
I
A
T
A
R
R
E
Y
E
K
L
Q
Q
E
V
Nematode Worm
Caenorhab. elegans
P34540
815
91875
G400
A
V
S
E
V
S
G
G
S
T
P
L
M
E
R
Sea Urchin
Strong. purpuratus
P35978
1031
117504
Y454
L
S
S
M
Q
R
D
Y
E
L
L
Q
S
Q
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
P48467
928
102392
L465
A
A
A
A
E
R
Q
L
R
E
T
K
E
E
L
Conservation
Percent
Protein Identity:
100
89.8
85.5
98.3
N.A.
98
69.8
N.A.
75.2
26.3
24.8
76.8
N.A.
62
63.2
45.3
61.4
Protein Similarity:
100
89.8
86.4
98.9
N.A.
99.1
81.6
N.A.
86.4
45.3
45.5
86.9
N.A.
77.6
77.9
61.3
74.7
P-Site Identity:
100
6.6
6.6
100
N.A.
100
66.6
N.A.
66.6
6.6
6.6
93.3
N.A.
46.6
53.3
13.3
46.6
P-Site Similarity:
100
20
20
100
N.A.
100
73.3
N.A.
80
53.3
46.6
100
N.A.
80
93.3
13.3
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
31.7
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
52.5
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
33.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
53.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
14
54
7
20
0
0
0
0
14
0
0
0
7
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
14
47
0
7
7
0
0
0
7
0
% D
% Glu:
0
14
7
7
7
0
27
0
54
7
0
14
34
74
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
7
7
7
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% H
% Ile:
14
0
0
0
0
0
0
14
0
0
27
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
14
40
14
7
0
0
0
% K
% Leu:
47
0
0
14
7
0
0
20
0
7
34
7
7
0
60
% L
% Met:
0
0
0
7
0
0
0
0
0
0
7
0
7
0
14
% M
% Asn:
14
0
7
0
0
7
14
7
0
7
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% P
% Gln:
14
0
20
0
14
0
7
7
0
14
0
60
7
7
0
% Q
% Arg:
0
0
0
0
54
60
0
0
7
0
0
0
7
0
7
% R
% Ser:
0
20
54
0
0
7
0
0
7
0
0
0
20
0
0
% S
% Thr:
0
0
7
40
14
7
0
0
0
14
7
14
14
14
0
% T
% Val:
0
14
0
0
7
0
0
0
0
0
7
0
0
0
20
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
14
0
0
0
47
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _